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1. Ansorge, Zur Ausscheidung von peptiden in menschlichen Harn, Hoppe Seyler Z Physiol Chem, № 348, с. 334
   https://doi.org/10.1515/bchm2.1967.348.1.334
2. Asatoor, Peptiduria in the Fanconi syndrome in peptide transport and hydrolysis, № 50, с. 287
3. Asperger, Die Psychopathologie des coeliakiekranken Kindes, Ann Pediatr, № 197, с. 346
4. Bauer, Regulation of degradation of thyrotropin releasing hormone by thyroid hormones, Nature, № 249, с. 591
   https://doi.org/10.1038/259591a0
5. Bourguignon, Urinary gonadotrophins and luteinizing hormone-releasing hormone (LHRH) like immunoreactivity during three normal reproductive cycles, Acta Endocrinol, № 86, с. 14
   https://doi.org/10.1530/acta.0.0860015
6. Brantl, A material with opioid activity in bovine milk and milk products, Naunyn-Schmiedebergs Arch Pharmacol, № 306, с. 301
   https://doi.org/10.1007/BF00507118
7. Bronstein, Enzymatic digestion of gliadin: The effect of the resultant peptides in adult coeliac disease, Clin Chim Acta, № 14, с. 141
   https://doi.org/10.1016/0009-8981(66)90080-5
8. Chalmers, Fat-mobilizing and ketogenic activity of urine extracts: Relation to corticotrophin and growth hormone, Lancet, № ii, с. 6
   https://doi.org/10.1016/S0140-6736(60)92658-1
9. Coleman, Calcium studies and their relationship to coeliac disease in autistic patients, с. 197
10. Coy, Effect of anorexogenic peptide on gastric and pancreatic secretion, J Physiol (Lond), № 314, с. 225
    https://doi.org/10.1113/jphysiol.1981.sp013703
11. Dohan, More on coeliac disease as a model for schizophrenia, Biol Psychiatry, № 18, с. 561
12. Ehrensing, Effects of MIF-I and TRH on the brain, с. 155
13. Folstein, Infantile autism: A genetic study of 21 twin pairs, J Child Psychol Psychiatry, № 18, с. 297
    https://doi.org/10.1111/j.1469-7610.1977.tb00443.x
14. Gardner, Evidence for, and implications of passage of intact peptides across the intestinal mucosa, Biochem Soc Trans, № 11, с. 810
    https://doi.org/10.1042/bst0110810
15. Gilberg, Childhood psychosis and urinary excretion of peptides and protein-associated peptide complexes, J Autism Dev Disord, № 12, с. 229
    https://doi.org/10.1007/BF01531369
16. Griffiths, Peptidase inactivation of hypothalamic releasing hormone, Horm Res, № 7, с. 179
    https://doi.org/10.1159/000178727
17. Griffiths, The effect of gonadectomy and gonadal steroids on the activity of hypothalamic peptidases inactivating luteinizing hormone-releasing hormone (LHRH), Brain Res, № 88, с. 384
    https://doi.org/10.1016/0006-8993(75)90404-7
18. Griffiths, Translocation of intracellular glutathione to membrane-bound glutamyltranspeptidase as a discrete step in the gamma-glutamyl cycle. Glutathionurea after inhibition of transpeptidase, № 76, с. 268
19. Gross, Dermatomyositis: Urinary chromatographic finding by alkaline autoanalysis for peptides, Clin Chem, № 19, с. 1412
    https://doi.org/10.1093/clinchem/19.12.1412
20. Hansson, Ausshceidung von peptiden in menschlichen Harn. Das verhalten isolierten peptidfractionen gegenüber proteolytischen enzymen, Hoppe Seylers Z Physiol Chem, № 348, с. 347
    https://doi.org/10.1515/bchm2.1967.348.1.347
21. Hemnings, The entry into the brain of large molecules derived from dietary protein, № 200, с. 175
22. Hui, Beta-endorphin inhibits met-enkephalin breakdown by a brain amino-peptidase. Structure activity relationship, Biochem Biophys Res Commun, № 105, с. 1482
    https://doi.org/10.1016/0006-291X(82)90955-X
23. Israngkun, Pattern of urinary putative neuropeptides in control and autistic subjects, Clin Chem, № 29, с. 1287
24. Israngkun, Pattern of urinary putative neuropeptides in autistic and control subjects, № 45, с. 1570
25. Jansson, Schizophren psykosbild avklingade nær pasienten gavs glutenfri kost, Lækartidningen, № 81, с. 148
26. Kanner, Autistic disturbances of affective contact, Nerv Child, № 2, с. 217
27. Kastin, Peripheral administration of hypothalamic peptides results in CNS changes, Pharmacol Res Commun, № 10, с. 293
    https://doi.org/10.1016/S0031-6989(78)80025-3
28. Kuhl, The activity of an LHRH-degrading enzyme in the anterior pituitary during the oestrus cycle and its alteration by injection of sex hormones, Acta Endocrinol, № 87, с. 476
    https://doi.org/10.1530/acta.0.0870476
29. Loukas, Opioid activities and structures of alpha-casein derived exorphines, Biochemistry, № 22, с. 238
    https://doi.org/10.1021/bi00288a034
30. Matthews, Uptake of a series of neutral dipeptides including 1 -alany l-1 -alanine, glycyl-glycine and glycyl-sarcosine by hamster jejunum in vitro, Clin Sci, № 67, с. 541
    https://doi.org/10.1042/cs0670541
31. Marhci, Child autism and gluten intolerance, Acta Paediatr Scand, № 63, с. 102
32. McGeer, Inhibition of angiotensin converting enzyme by substance P, Neurosci Lett, № 14, с. 105
    https://doi.org/10.1016/0304-3940(79)95353-9
33. Mellander, Enzyme resistance and metal binding of phosphorylated peptides, IEFN, № 11, с. 569
34. Noguchi, Some nutritional and physiological factors affecting the urinary secretion of acid soluble peptides in rats and women, Agric Biol Chem, № 46, с. 2821
    https://doi.org/10.1271/bbb1961.46.2821
35. Ornitz, The syndrome of autism. Critical review, Am J Psychiatry, № 113, с. 609
36. Reichelt, Childhood autism. New perspectives, Glasskulen, с. 5
37. Reichelt, Histamine dependent formation of N-acetyl-aspartyl peptides in mouse brain, J Neurochem, № 21, с. 849
    https://doi.org/10.1111/j.1471-4159.1973.tb07529.x
38. Reichelt, Humeral control of appetite, Neuroscience, № 3, с. 2107
39. Reichelt, Biologically active peptide-containing fractions in schizophrenia and childhood autism, Adv Biochem Psychopharmacol, № 28, с. 627
40. Reichelt, The isolation and characterization of an insulin-releasing tetrapeptide from urines of patients with lipoatrophic diabetes, Biochem Biophys Res Commun, № 122, с. 103
    https://doi.org/10.1016/0006-291X(84)90445-5
41. Rimland
42. Root, Urinary excretion of immunoreactive gonadotropin releasing hormone-like material in prepubertal and pubertal children, J Clin Endocrinol Metab, № 44, с. 909
    https://doi.org/10.1210/jcem-44-5-909
43. Saelid, Peptide containing fractions in depression, Biol Psychiatry, № 20, с. 245
    https://doi.org/10.1016/0006-3223(85)90054-X
44. Schally, Inhibition of sham feeding-induced gastric secretion and serum hormonal responses by analogs of pyro-glu-his-gly-OH, № 170, с. 264
45. Trygstad, Patterns of peptides and protein-associated peptide complexes in psychiatric disorders, Br J Psychiatry, № 136, с. 59
    https://doi.org/10.1192/bjp.136.1.59
46. Wauters, Excretion of pyrrolidonyl peptides and amino acid conjugates in a patient with coeliac disease and cystic fibrosis, с. 473
47. Weeke, Rocket immunoelectrophoresis, с. 37
48. Weeke, Crossed immunoelectrophoresis, с. 47
49. Weiss, The quantitative relationship of urinary peptide hydroxyproline excretion to collagen degradation, J Clin Invest, № 48, с. 1
    https://doi.org/10.1172/JCI105957
50. Ziesler, Transport and distribution of hom*ocarnosine after intracerebroventricular and intravenous injection in the rat, Neurochem Res, № 9, с. 637
    https://doi.org/10.1007/BF00964510
51. Zioudrou, Opioid peptides derived from food proteins, J Biol Chem, № 254, с. 2446
    https://doi.org/10.1016/S0021-9258(17)30243-0

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